Polynucleotide Treatments: The New Age of Skin Rejuvenation
Move over, Botox—there’s a new anti-aging powerhouse in town. Polynucleotide treatments, often called the “salmon-sperm facial” (yes, really), are the latest innovation in skin rejuvenation. These treatments harness the power of DNA fragments extracted from salmon to repair, hydrate, and revitalize the skin on a cellular level.
Already a staple in Korean and European skincare, polynucleotides are now making waves in the U.S. beauty industry. But what exactly are they, and should you be booking your first treatment? Let’s break it all down.
What Are Polynucleotides?
Polynucleotides (PNs) are DNA molecules that work by stimulating fibroblasts—the cells responsible for producing collagen and elastin. Unlike traditional fillers that simply plump the skin, polynucleotide treatments actually repair and regenerate tissue, making them ideal for:
✅ Deep hydration and skin barrier repair
✅ Smoothing fine lines and wrinkles
✅ Improving skin elasticity and firmness
✅ Reducing redness, rosacea, and acne scars
✅ Enhancing overall skin tone and glow
Think of it as a cellular reset for your skin.
How Polynucleotide Treatments Work
These treatments are typically administered through microinjections, similar to mesotherapy. A practitioner injects small amounts of the polynucleotide serum into targeted areas, triggering collagen production and tissue repair.
💉 Treatment Process:
- Numbing cream is applied for comfort.
- The serum is injected into the skin using fine needles or a microneedling device.
- Mild redness and swelling may occur, but downtime is minimal.
- Full results develop over 4-6 weeks, with optimal benefits after 2-3 sessions.
Most people see brighter, plumper skin within a few days, with continued improvement as collagen builds over time.
Best At-Home Products to Boost Polynucleotide Results
While professional polynucleotide treatments work at a deep level, you can enhance and prolong your results with high-performance at-home skincare. Here are four top picks for every budget:
💰 Budget-Friendly: COSRX Snail Mucin 96% Power Essence ($35)
This K-beauty favorite is packed with healing and hydrating properties, perfect for post-treatment skin recovery.
💡 Pro Tip: Apply twice daily for a dewy, plump finish that enhances collagen production.
💲 Mid-Range: Neogen Real Ferment Micro Serum ($38)
A probiotic-rich serum that strengthens the skin barrier, improving elasticity and moisture retention.
💡 Pro Tip: Use after a hydrating toner to help nutrients absorb more effectively.
💎💎 Luxury Splurge: Augustinus Bader The Rich Cream ($308)
A cult-favorite moisturizer infused with growth factors to support cell renewal and hydration.
💡 Pro Tip: Apply at night for deep overnight skin repair, especially after a professional PN treatment.
How to Maximize Your Polynucleotide Treatment Results
📌 Stay Hydrated: Drink plenty of water to support cell regeneration.
📌 Use SPF Daily: Polynucleotides increase cell turnover, making skin more sensitive to UV damage.
📌 Pair with LED Therapy: Red light therapy can accelerate collagen production for even better results.
📌 Avoid Harsh Exfoliants: Give your skin a break from retinol and acids for a few days post-treatment.
📌 Consistency is Key: For long-term benefits, schedule maintenance treatments every 6-12 months.
Polynucleotide treatments are changing the game for anti-aging skincare, offering a natural, regenerative approach that strengthens skin from within. Whether you're looking for deep hydration, scar healing, or a collagen boost, this treatment could be your new skincare obsession.
Would you try the “salmon DNA facial”? Let’s talk in the comments!